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KMID : 0981820070270030188
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Korean Journal of Laboratory Medicine
2007 Volume.27 No. 3 p.188 ~ p.191
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Acute Hemolysis and Renal Failure caused by Hepatitis A Infection with Underlying Glucose-6-Phosphate Dehydrogenase Deficiency
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Jekarl Dong-Wook
Oh Eun-Jee
Park Yeon-Joon
Han Kyung-Ja
Lee Sung-Won
Park Chong-Won
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Abstract
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Although glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder worldwide, it has rarely been reported among Korean. The patient was previously healthy 39 yr old male who showed severe hemolytic anemia and acute renal failure accompanied by hyperbilirubinemia after hepatitis A infection. The additional studies for differential diagnosis of hemolytic anemia showed a moderate deficiency of G6PD enzyme. Because hepatitis A infection in patient with G6PD deficiency present much more severe clinical symptoms, G6PD enzyme should be examined in patients with triggering factors of hemolysis such as hepatitis A infection. (Korean J Lab Med 2007;27:188-91)
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KEYWORD
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Glucose-6-phosphate dehydrogenase deficiency, Hepatitis A virus, Hemolytic anemia, Acute renal failure
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